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Lactate racemase : ウィキペディア英語版 | Lactate racemase The lactate racemase enzyme () is involved in pyruvate metabolism. It is classified under the isomerase, racemase, epimerase, and enzyme acting on hydroxyl acids and derivatives classes of enzymes.〔(【引用サイトリンク】title=DBGET Result: ENZYME 5.1.2.1 )〕 It is found in certain halophilic archaea, such as ''Haloarcula marismortui'' and in a few species of bacteria, such as several ''Lactobacillus'' species (which produce D- and L-lactate), including ''Lactobacillus sakei'', ''Lactobacillus curvatus'', ''Lactobacillus plantarum'', as well as in non-lactic acid bacteria such as ''Clostridium beijerinckii''. ==Structure and properties== The molecular weight of lactate racemase (Lar) differs in the various organisms in which it has been found, ranging from 25,000 to 82,400 g/mol.〔(【引用サイトリンク】title=BRENDA: Entry of Lactate racemase(EC-Number 5.1.2.1 ) )〕 One molecule of the enzyme contains two iron atoms. The optimal pH for its activity is 5.8-6.2 in ''L. sake''.〔 Few biochemical studies have been performed on the enzyme because it is highly sensitive to oxidation.〔 The gene sequence encoding the enzyme is not known from any species, and the N-terminal sequence has not been determined.
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